duodenectomy Excision or the surgical removal of the duodenum. The duodenum is the first or proximal (nearest) portion of the small intestine, extending from the pylorus (opening in a vertebrate from the stomach into the intestine) to the jejunum (the portion of the small intestine that extends from the duodenum to the ileum), so called because it... Found on http://www.wordinfo.info/words/index/info/view_unit/682/