Used in cytogenetics, colcemid, also known as demecolcine, is related to colchicine but it is less toxic. It depolymerises microtubules and limits microtubule formation (inactivates spindle fibre formation), thus arresting cells in metaphase and allowing cell harvest and karyotyping to be performed. ==Mechanism of Action== Colcemid is a microtubul...
Found on
http://en.wikipedia.org/wiki/Colcemid
<drug> Methylated derivative of colchicine. ... (18 Nov 1997) ...
Found on
http://www.encyclo.co.uk/local/20973
(kol´sĕ-mid) trademark for a preparation of demecolcine, a cytotoxic alkaloid used in chromosome analysis.
Found on
http://www.encyclo.co.uk/local/21001
No exact match found.
