
<chemical> A peripheral inhibitor of dopa decarboxylase. It is given in parkinsonism along with levodopa to inhibit the conversion of levodopa to dopamine in the periphery, thereby reducing the peripheral adverse effects, increasing the amount of levodopa that reaches the central nervous system, and reducing the dose needed. It has no antipar...
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http://www.encyclo.co.uk/local/20973

(kahr″bĭ-do´pә) an inhibitor of the decarboxylation of levodopa in peripheral tissues; it does not cross the blood-brain barrier and is used in combination with levodopa to control the symptoms of Parkinson disease. In the presence of carbidopa, levodopa enters the brain in larger quantities, thus avoid...
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http://www.encyclo.co.uk/local/21001

The ingredient in Sinemet which prevents the breakdown of the levodopa in the body before it can reach the brain.
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Type: Term Pronunciation: kar′bi-dō′pă Definitions: 1. A dopa decarboxylase inhibitor that does not enter the brain used in conjunction with levodopa in the treatment of Parkinson disease to reduce L-dopa dosage and mitigate side effects.
Found on
http://www.medilexicon.com/medicaldictionary.php?t=14210
No exact match found.