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mondofacto - Online Medical Dictionary Category: Health and Medicine > Medical Dictionary Date & country: 26/01/2008, UK Words: 116197

fibrinogenopenia
A concentration of fibrinogen in the blood that is less than the normal. ... Origin: fibrinogen + G. Penia, poverty ... (05 Mar 2000) ...

fibrinogenous
<physiology> Possessed of properties similar to fibrinogen; capable of forming fibrin. Pertaining to fibrinogen, producing fibrin. ... (12 May 2002) ...

fibrinogens, abnormal
Fibrinogens which have a functional defect as the result of one or more amino acid substitutions in the amino acid sequence of normal fibrinogen. Abnormalities of the fibrinogen molecule may impair any of the major steps involved in the conversion of fibrinogen into stabilised fibrin, such as cleavage of the fibrinopeptides by thrombin, polymerizat …

fibrinoid
1. Resembling fibrin. ... 2. A deeply or brilliantly acidophilic, homogeneous, refractile, proteinaceous material that: 1) is frequently formed in the walls of blood vessels and in connective tissue of patients with such diseases as disseminated lupus erythematosus, polyarteritis nodosa, scleroderma, dermatomyositis, and rheumatic fever; 2) is somet …

fibrinoid necrosis
Necrosis in which the necrotic tissue has some staining reactions resembling fibrin and becomes deeply eosinophilic, homogenous, and refractile. ... (05 Mar 2000) ...

fibrinokinase
Name proposed for the enzyme that converts plasminogen to plasmin; subsequently called urokinase, but now called plasminogen activator. ... Synonym: fibrinolysokinase. ... (05 Mar 2000) ...

fibrinolysin
Synonym: plasmin. ... (05 Mar 2000) ...

fibrinolysis
<haematology> Solubilisation of fibrin in blood clots, chiefly by the proteolytic action of plasmin. ... Origin: Gr. Lysis = dissolution ... (12 Nov 1997) ...

fibrinolysokinase
Synonym for fibrinokinase ... Name proposed for the enzyme that converts plasminogen to plasmin; subsequently called urokinase, but now called plasminogen activator. ... Synonym: fibrinolysokinase. ... (05 Mar 2000) ...

fibrinolytic
Pertaining to, characterised by or causing the dissolution of fibrin by enzymatic action ... Origin: Gr. Lysis = dissolution ... (18 Nov 1997) ...

fibrinolytic agent
Fibrinolysin or agents that convert plasminogen to fibrinolysin. They may be endogenous or exogenous like the bacterial enzymes used in thromboembolism. ... (12 Dec 1998) ...

fibrinolytic purpura
Purpura in which the bleeding is associated with rapid fibrinolysis of the clot. ... (05 Mar 2000) ...

fibrinopeptide
<protein> Very negatively charged peptide fragments cleaved from fibrinogen by thrombin. Two peptides (A and B) are produced from each fibrinogen molecule. ... A: This is released as a part of the clotting process. Increased levels may be seen in DIC, lupus, cellulitis and leukaemia. ... (09 Oct 1997) ...

fibrinopeptide a
Two small peptide chains removed from the n-terminal segment of the alpha chains of fibrinogen by the action of thrombin during the blood coagulation process. Each peptide chain contains 18 amino acid residues. In vivo, fibrinopeptide a is used as a marker to determine the rate of conversion of fibrinogen to fibrin by thrombin. ... (12 Dec 1998) ...

fibrinopeptide b
Two small peptide chains removed from the n-terminal segment of the beta chains of fibrinogen by the action of thrombin. Each peptide chain contains 20 amino acid residues. The removal of fibrinopeptides b is not required for coagulation. ... (12 Dec 1998) ...

fibrinopurulent
Pertaining to pus or suppurative exudate that contains a relatively large amount of fibrin. ... (05 Mar 2000) ...

fibrinopurulent inflammation
A purulent inflammation in which the exudate contains an unusually large amount of fibrin; also, a fibrinous or serofibrinous inflammation in which the accumulation of large numbers of polymorphonuclear leukocytes results in liquefactive necrosis of tissue and the formation of pus with a relatively large quantity of fibrin. ... (05 Mar 2000) ...

fibrinoscopy
The chemical and physical examination of the fibrin of exudates, blood clots, etc. ... Origin: fibrino-+ G. Skopeo, to view ... (05 Mar 2000) ...

fibrinous
Pertaining to or composed of fibrin. ... (05 Mar 2000) ...

fibrinous adhesion
An adhesion that consists of fine threads of fibrin resulting from an exudate of plasma or lymph, or an extravasation of blood. ... (05 Mar 2000) ...

fibrinous bronchitis
Inflammation of the bronchial mucous membrane, accompanied by a fibrinous exudation, which often forms a cast of the bronchial tree with severe obstruction of air flow. ... Synonym: plastic bronchitis, pseudomembranous bronchitis. ... (05 Mar 2000) ...

fibrinous cast
A yellow cast that somewhat resembles a waxy cast; more likely to occur in the urine of certain patients with acute nephritis. ... (05 Mar 2000) ...

fibrinous degeneration
A process resulting in poorly defined, deeply acidophilic, homogeneous refractile deposits with some staining reactions that resemble fibrin, occurring in connective tissue, blood vessel walls, and other sites. ... (05 Mar 2000) ...

fibrinous inflammation
An exudative inflammation in which there is a disproportionately large amount of fibrin. ... (05 Mar 2000) ...

fibrinous iritis
Acute inflammation of the iris, with profuse exudate; occurs in uveitis of tertiary syphilis. ... (05 Mar 2000) ...

fibrinous lymph
A euplastic or croupous lymph. ... (05 Mar 2000) ...

fibrinous pericarditis
Acute pericarditis with fibrinous exudate. ... See: bread-and-butter pericardium. ... Synonym: hairy heart, pericarditis villosa, shaggy pericardium. ... (05 Mar 2000) ...

fibrinous pleurisy
Synonym for dry pleurisy ... Pleurisy with a fibrinous exudation, without an effusion of serum, resulting in adhesion between the opposing surfaces of the pleura. ... Synonym: adhesive pleurisy, fibrinous pleurisy, plastic pleurisy. ... (05 Mar 2000) ...

fibrinous polyp
A misnomer for a mass of fibrin retained within the uterine cavity after childbirth. ... (05 Mar 2000) ...

fibrinuria
The passage of urine that contains fibrin. ... Origin: fibrin + G. Ouron, urine ... (05 Mar 2000) ...

fibrists
Organic soils (peats) in which plant remains show very little decomposition and retain their original shape, more than two-thirds of the fibres remain after rubbing the materials between the fingers. ... (09 Oct 1997) ...

fibro-
Fibr- ... Fibre. ... Origin: L. Fibra ... (05 Mar 2000) ...

fibro-osteoma
<tumour> An osteoma in which the neoplastic bone-forming cells are situated within a relatively abundant stroma of fibrous tissue. ... (05 Mar 2000) ...

fibroadenoma
<oncology, tumour> A benign solid growth, usually found in the breast. ... (09 Oct 1997) ...

fibroadipose
Relating to or containing both fibrous and fatty structures. ... Synonym: fibrofatty. ... (05 Mar 2000) ...

fibroareolar
Denoting connective tissue that is both fibrous and areolar in character. ... (05 Mar 2000) ...

fibroblast
<pathology> Resident cell of connective tissue, mesodermally derived, that secretes fibrillar procollagen, fibronectin and collagenase. ... (18 Nov 1997) ...

fibroblast growth factor
<growth factor> Acidic fibroblast growth factor (alpha FGF, HBGF 1) and basic FGF (beta FGF, HBGF 2) are the two founder members of a family of structurally related growth factors for mesodermal or neuroectodermal cells. ... Synonym: heparin binding growth factor. ... Acronym: FGF ... (18 Nov 1997) ...

fibroblast growth factor receptor
Family of receptor tyrosine kinases for fibroblast growth factor. ... (18 Nov 1997) ...

fibroblast growth factor, acidic
<chemical> A growth factor which has been isolated from a variety of cells. It contains 154 amino acid residues and has potent heparin-binding activity. Heparin potentiates the biological activities of afgf. The growth factor is an extremely potent inducer of DNA synthesis in a variety of normal diploid mammalian cell types from mesoderm and …

fibroblast growth factor, basic
A single-chain polypeptide of approximately 15-16 kD which has been isolated from a variety of cells. It has a 55% amino acid residue identity to acidic fibroblast growth factor and has potent heparin-binding activity. However, in contrast to the acidic fibroblast growth factor, heparin does not potentiate the biological activities of bfgf. The gro …

fibroblast interferon
Synonym for interferon-beta ... <cytokine> One of the type I interferons produced by fibroblasts in response to stimulation by live or inactivated virus or by double-stranded RNA. It is a cytokine with antiviral, antiproliferative, and immunomodulating activity. ... Synonym: fibroblast interferon. ... Pharmacological action: adjuvants, immunolog …

fibroblastic
<pathology> Many types of cultured cell become fibroblastic in appearance this does not mean that they are fibroblasts. ... (18 Nov 1997) ...

fibroblasts
Connective tissue cells which differentiate into chondroblasts, collagenoblasts, and osteoblasts. ... (12 Dec 1998) ...

fibrocarcinoma
Synonym for scirrhous carcinoma ... <tumour> A hard carcinoma, fibrous in nature, resulting from a desmoplastic reaction by the stromal tissue to the presence of the neoplastic epithelium. ... Synonym: fibrocarcinoma. ... (05 Mar 2000) ...

fibrocartilaginous
Relating to or composed of fibrocartilage. ... (05 Mar 2000) ...

fibrocartilaginous ring
Of tympanic membrane, the thickened portion of the circumference of the tympanic membrane that is fixed in the tympanic sulcus. ... Synonym: annulus fibrocartilagineus membranae tympani, Gerlach's annular tendon. ... (05 Mar 2000) ...

fibrocartilago
Synonym: fibrocartilage. ... (05 Mar 2000) ...

fibrocartilago basalis
Synonym for basilar cartilage ... The cartilage filling the foramen lacerum. ... Synonym: basilar fibrocartilage, fibrocartilago basalis. ... (05 Mar 2000) ...

fibrocartilago interarticularis
Synonym for articular disc ... A plate or ring of fibrocartilage attached to the joint capsule and separating the articular surfaces of the bones for a varying distance, sometimes completely; it serves to adapt two articular surfaces that are not entirely congruent. ... Synonym: discus articularis, articular disk, fibrocartilago interarticularis, fib …

fibrocartilago intervertebralis
Synonym for intervertebral disc ... <anatomy> The intervertebral discs or nucleus pulposus are a fibro-cartilaginous disc that lie between the vertebral bodies in the spine. ... These disks are composed of a central gelatinous-like material that provide a cushioning or shock absorbing quality to the spinal column to axial stress. Discs may hern …

fibrocaseous peritonitis
Peritonitis characterised by caseation and fibrosis, usually caused by the tubercle bacillus. ... (05 Mar 2000) ...

fibrocellular
Both fibrous and cellular. ... (05 Mar 2000) ...

fibrochondritis
Inflammation of a fibrocartilage. ... (05 Mar 2000) ...

fibrochondroma
<tumour> A benign neoplasm of cartilaginous tissue, in which there is a relatively unusual amount of fibrous stroma. ... (05 Mar 2000) ...

fibrocongestive
Term sometimes used to indicate the general condition of an organ or tissue in which acute or chronic, persistent congestion has resulted in degeneration and necrosis of cells and replacement with connective tissue elements, as in chronic congestive splenomegaly. ... (05 Mar 2000) ...

fibrocyst
Any cystic lesion circumscribed by or situated within a conspicuous amount of fibrous connective tissue. ... (05 Mar 2000) ...

fibrocystic
Pertaining to or characterised by the presence of fibrocysts. ... (05 Mar 2000) ...

fibrocystic condition of the breast
A benign disease common in women of the third, fourth, and fifth decades characterised by formation, in one or both breasts, of small cysts containing fluid which may appear as blue dome cysts; associated with stromal fibrosis and with variable degrees of intraductal epithelial hyperplasia and sclerosing adenosis. ... Synonym: cystic hyperplasia of …

fibrocystic disease
<oncology, surgery> A noncancerous breast condition in which multiple cysts or lumpy areas develop in one or both breasts. It can be accompanied by discomfort or pain that fluctuates with the menstrual cycle. May be exacerbated by caffeine use. Large cysts can be treated by aspiration of the fluid they contain. ... (04 Nov 1997) ...

fibrocystic disease of breast
A chronic disorder comprising three variants which range from lesions consisting primarily of an overgrowth of fibrous tissue to those characterised by dominance of the proliferation of the epithelial parenchyma to a form of dysplasia characterised by both stromal and epithelial hyperplasia with the formation of cysts. ... (12 Dec 1998) ...

fibrocystic disease of the pancreas
Synonym for cystic fibrosis ... <chest medicine> A generalised disorder of infants, children and young adults, in which there is widespread dysfunction of the exocrine glands, characterised by signs of chronic pulmonary disease (due to excess mucus production in the respiratory tract), pancreatic deficiency, abnormally high levels of electroly …

fibrocystoma
<tumour> A benign neoplasm, usually derived from glandular epithelium, characterised by cysts within a conspicuous fibrous stroma. ... (05 Mar 2000) ...

fibrocyte
<pathology> Stellate shaped cells present in connective tissue capable of forming collagen, an essential component of wound healing. The inactive form of the cell is referred to as a fibrocyte. ... (27 Sep 1997) ...

fibrodysplasia
Abnormal development of fibrous connective tissue. ... Fibrodysplasia ossificans progressiva, a generalised disorder of connective tissue in which bone replaces tendons, fasciae, and ligaments; a lethal genetic disorder inferred from indirect evidence to have autosomal dominant inheritance. ... See: fibrous dysplasia of bone. ... (05 Mar 2000) ...

fibroelastic
Composed of collagen and elastic fibres. ... (05 Mar 2000) ...

fibroelastic membrane of larynx
A layer of fibrous and elastic fibres, taking the place of the submucosa in the larynx. It is divided by the laryngeal ventricle into two parts: the quadrangular membrane superiorly and the conus elasticus inferiorly. ... Synonym: membrana fibroelastica laryngis. ... (05 Mar 2000) ...

fibroelastosis
Excessive proliferation of collagenous and elastic fibrous tissue. ... (05 Mar 2000) ...

fibroenchondroma
<tumour> An enchondroma in which the neoplastic cartilage cells are situated within an abundant fibrous stroma. ... (05 Mar 2000) ...

fibroepithelial polyp
Synonym for skin tag ... A polypoid outgrowth of both epidermis and dermal fibrovascular tissue, common terminology for any small benign cutaneous lesion. ... Synonym: acrochordon, fibroepithelial polyp, fibroma molle, senile fibroma, soft wart. ... (05 Mar 2000) ...

fibroepithelioma
<tumour> A skin tumour composed of fibrous tissue intersected by thin anastomosing bands of basal cells of the epidermis; may give rise to basal cell carcinoma of the nodular type. ... Synonym: Pinkus tumour. ... (05 Mar 2000) ...

fibrofatty
Synonym for fibroadipose ... Relating to or containing both fibrous and fatty structures. ... Synonym: fibrofatty. ... (05 Mar 2000) ...

fibrofolliculoma
<tumour> Neoplastic proliferation of the fibrous sheath of the hair follicle, with solid extensions of the epithelium of the follicular infundibulum; multiple fibrofolliculoma's may be familial. ... (05 Mar 2000) ...

fibrogenesis
The production or development of fibres. ... (05 Mar 2000) ...

fibrogliosis
A cellular reaction within the brain, usually in response to a penetrating injury, in which both astrocytes and fibroblasts participate and which culminates in a fibrous and glial scar. ... Origin: fibro-+ G. Glia, glue, + -osis, condition ... (05 Mar 2000) ...

fibrohyaline tissue
Synonym for chondroid tissue ... In an adult, tissue resembling cartilage. ... In an embryo, an early stage in cartilage formation. ... Synonym: fibrohyaline tissue, pseudocartilage. ... (05 Mar 2000) ...

fibroid
<gynaecology, oncology, tumour> Benign smooth muscle tumours of the uterus. May cause irregular vaginal bleeding. ... Synonym: leiomyomata. ... (27 Sep 1997) ...

fibroid adenoma
Synonym for fibroadenoma ... <oncology, tumour> A benign solid growth, usually found in the breast. ... (09 Oct 1997) ...

fibroid cataract
A sclerotic hardening of the capsule of the lens, following exudative iridocyclitis. ... (05 Mar 2000) ...

fibroid inflammation
Synonym for atrophic inflammation ... A form of chronic inflammation or repeated episodes of acute inflammation in which the continued or recurrent proliferation of fibroblasts results in the formation of fibrous tissue that eventually contracts and leads to compression and atrophy of parenchymal tissue. ... Synonym: fibroid inflammation. ... (05 Mar …

fibroid lung
Chronic interstitial pneumonia in a lung. ... (05 Mar 2000) ...

fibroid tumour
Old term for certain fibromas and leiomyomas. ... (05 Mar 2000) ...

fibroidectomy
<procedure> Removal of a fibroid tumour. ... Synonym: fibromectomy. ... Origin: fibroid + G. Ektome, excision ... (05 Mar 2000) ...

fibroin
<biology> Structural protein of silk, one of the first to be studied with X-ray diffraction. It has a repeat sequence GSGAGA and is unusual in that it consists almost entirely of stacked antiparallel _ pleated sheets. ... (18 Nov 1997) ...

fibrokeratoma
A keratotic cutaneous polyp containing abundant connective tissue. ... (05 Mar 2000) ...

fibrolamellar hepatocarcinoma
<radiology> Distinct from usual hepatocellular carcinoma, younger patients, non-cirrhotic livers, better prognosis, not associated with oral contraceptives ... (12 Dec 1998) ...

fibrolamellar liver cell carcinoma
<tumour> Primary hepatic carcinoma in which malignant hepatocytes are intersected by fibrous lamellated bands. ... Synonym: oncocytic hepatocellular tumour. ... (05 Mar 2000) ...

fibrolase
<enzyme> From the venom of agkistrodon contortrix; direct-acting fibrin-degrading zinc-metalloproteinase; mw 23-25kda; cleaves primarily the aa-chain of human fibrinogen and fibrin between the lys-413 and leu-414 position; the bb chain is cleaved more slowly; gamma chain is minimally affected ... Registry number: EC 3.4.24.- ... Synonym: agkist …

fibroleiomyoma
<tumour> A leiomyoma containing non-neoplastic collagenous fibrous tissue, which may make the tumour hard; fibroleiomyoma usually arises in the myometrium, and the proportion of fibrous tissue increases with age. ... Synonym: fibroid, leiomyofibroma. ... (05 Mar 2000) ...

fibrolipoma
<tumour> A lipoma with an abundant stroma of fibrous tissue. ... Synonym: lipoma fibrosum. ... (05 Mar 2000) ...

fibroma
<oncology, tumour> A benign (non-cancerous) tumour which consists of fibrous tissues or connective tissue. ... (09 Oct 1997) ...

fibroma molle
Synonym for skin tag ... A polypoid outgrowth of both epidermis and dermal fibrovascular tissue, common terminology for any small benign cutaneous lesion. ... Synonym: acrochordon, fibroepithelial polyp, fibroma molle, senile fibroma, soft wart. ... (05 Mar 2000) ...

fibroma molle gravidarum
Skin tags or polyps that develop on women during pregnancy and often disappear at term. ... (05 Mar 2000) ...

fibroma myxomatodes
Synonym for myxofibroma ... <tumour> A benign neoplasm of fibrous connective tissue that resembles primitive mesenchymal tissue. ... Synonym: fibroma myxomatodes, myxoma fibrosum. ... Origin: myxo-+ L. Fibra, fibre, + G. -oma, tumour ... (05 Mar 2000) ...

fibroma virus, rabbit
A species of leporipoxvirus causing subcutaneous localised swellings in rabbits, usually on the feet. ... (12 Dec 1998) ...

fibroma, desmoplastic
A extremely rare bone tumour characterised by abundant collagen formation and a fibrous stroma, without evidence of mitosis or pleomorphism. It appears on X-rays as an osteolytic lesion with well-defined margins and must be differentiated from primary fibrosarcoma of bone. (devita jr et al., cancer: principles & practice of oncology, 3d ed, p14 …

fibroma, ossifying
A benign, relatively slow-growing, central bone tumour, usually of the jaws (especially the mandible) which is composed of fibrous connective tissue within which bone is formed. ... (12 Dec 1998) ...

fibromatoid
A focus, nodule, or mass (of proliferating fibroblasts) that resembles a fibroma but is not regarded as neoplastic. ... (05 Mar 2000) ...

fibromatosis
1. A condition characterised by the occurrence of multiple fibromas, with a relatively large distribution. ... 2. Abnormal hyperplasia of fibrous tissue. ... (05 Mar 2000) ...

fibromatosis colli
A fibrous mass in the midportion of the sternocleidomastoid muscle; the mass may be a haematoma resulting from a birth injury and may cause torticollis. ... (05 Mar 2000) ...