Wortmannin, a steroid metabolite of the fungi Penicillium funiculosum, Talaromyces (Penicillium) wortmannii, is a specific, covalent inhibitor of phosphoinositide 3-kinases (PI3Ks). It has an in vitro inhibitory concentration (IC50) of around 5 nM, making it a more potent inhibitor than LY294002, another commonly used PI3K inhibitor. It displays a...
Found on
http://en.wikipedia.org/wiki/Wortmannin
Inhibitor of PI-3-kinases, and possibly other points in the Ras/MAP kinase signalling pathway.
Found on
http://www.encyclo.co.uk/visitor-contributions.php
No exact match found.
