In mammalian cells, vinculin is a membrane-cytoskeletal protein in focal adhesion plaques that is involved in linkage of integrin adhesion molecules to the actin cytoskeleton. Discovered independently by Benny Geiger and Keith Burridge, its sequence is 20%-30% similar to α-catenin, which serves a similar function. Vinculin is a 117-kDa cytoskelet...
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http://en.wikipedia.org/wiki/Vinculin
<cell biology> Protein (130 kD) isolated from muscle (cardiac and smooth), fibroblasts and epithelial cells. Associated with the cytoplasmic face of focal adhesions: may connect microfilaments to plasma membrane integral proteins through talin. ... (18 Nov 1997) ...
Found on
http://www.encyclo.co.uk/local/20973
Protein (130 kD) isolated from muscle (cardiac and smooth), fibroblasts and epithelial cells. Associated with the cytoplasmic face of focal adhesions: may connect microfilaments to plasma membrane integral proteins through talin.
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http://www.encyclo.co.uk/visitor-contributions.php
Type: Term Pronunciation: ving′kyū-lin Definitions: 1. A protein associated with actin microfilaments; found in intercalated discs of cardiac muscle and focal adhesion plaques; may have a role in how a tumor virus causes pleiotropic effects of transformation.
Found on
http://www.medilexicon.com/medicaldictionary.php?t=98657
No exact match found.
