A synaptosome is an isolated synaptic terminal from a neuron. Synaptosomes are obtained by mild homogenization of nervous tissue under isotonic conditions and subsequent fractionation using differential and density gradient centrifugation. Liquid shear detaches the nerve terminals from the axon and the plasma membrane surrounding the nerve termina...
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http://en.wikipedia.org/wiki/Synaptosome
<cell biology> A subcellular fraction prepared from tissues rich in chemical synapses, used in biochemical studies. Consists mainly of vesicles from presynaptic terminals. ... Origin: Gr. Soma = body ... (18 Nov 1997) ...
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A subcellular fraction prepared from tissues rich in chemical synapses, used in biochemical studies. Consists mainly of vesicles from presynaptic terminals.
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Type: Term Pronunciation: sin-ap′tō-sōm Definitions: 1. Membrane-bound sac containing synaptic vesicles that breaks away from axon terminals when brain tissue is homogenized under controlled conditions; such particles can be separated from other subcellular particles by differential and density gradient centrifugation. ...
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http://www.medilexicon.com/medicaldictionary.php?t=87491
synaptosome 1. A saclike structure formed by nerve endings at a synapse that remains intact after homogenization of nerve tissue. 2. A subcellular fraction prepared from tissues rich in chemical synapses, used in biochemical studies. It consists mainly of vesicles from presynaptic terminals.
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http://www.wordinfo.info/words/index/info/view_unit/2073/14
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