Sirolimus (INN/USAN), also known as rapamycin, is a macrolide (one of a group of drugs containing a macrolide ring) produced by the bacteria Streptomyces hygroscopicus. It has immunosuppressant functions in humans and is used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. It prevents activation of T c...
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http://en.wikipedia.org/wiki/Sirolimus
A drug used to keep the body from rejecting organ and bone marrow transplants. Sirolimus blocks certain white blood cells that can reject foreign tissues and organs. It also blocks a protein that is involved in cell division. It is a type of antibiotic, a type of immunosuppressant, and a type of serine/threonine kinase inhibitor. Sirolimus was prev...
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http://www.cancer.gov/dictionary?expand=S
(sĭ-ro´lĭ-mәs) a macrolide antibiotic obtained from Streptomyces hygroscopicus, having immunosuppressant properties; used to prevent rejection of kidney transplants. Administered orally.
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http://www.encyclo.co.uk/local/21001
Sirolimus: A naturally occurring substance discovered in a soil sample from Easter Island. Sirolimus was initially thought to hold promise as an antifungal antibiotic but this idea was dropped when sirolimus was unexpectedly found to have immunosuppressive activity. The US Food and Drug Administration in 1999 approved the use of sirolimus as an imm...
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http://www.medterms.com/script/main/art.asp?articlekey=24563
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