Sin'is·trous adjective [ See Sinister .] 1. Being on the left side; inclined to the left; sinistral. ' Sinistrous gravity.' Sir T. Browne. 2. Wrong; absurd; perverse. « A knave or fool can do no harm, even by the most sinistrous and absurd choice.... Found on http://www.encyclo.co.uk/webster/S/107