
Ryanodine is a poisonous alkaloid found in the South American plant Ryania speciosa (Salicaceae). It was originally used as an insecticide. The compound has extremely high affinity to the open-form ryanodine receptor, a group of calcium channels found in skeletal muscle, smooth muscle, and heart muscle cells. It binds with such high affinity to th...
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http://en.wikipedia.org/wiki/Ryanodine

<drug> A drug that blocks the release of calcium from the sarcoplasmic reticulum of skeletal muscle. Ryanodine binding proteins have also been found in the CNS. ... (17 Dec 1997) ...
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http://www.encyclo.co.uk/local/20973

Drug that blocks the release of calcium from the sarcoplasmic reticulum of skeletal muscle. Ryanodine-binding proteins have also been found in the CNS.
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Type: Term Pronunciation: rī-an′ō-dēn Definitions: 1. An alkaloid obtained from Ryania speciosa (family Flacourtiaceae); has a disruptive effect on calcium storage in cardiac and skeletal muscle, where it produces sustained contractions; used as an insecticide.
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http://www.medilexicon.com/medicaldictionary.php?t=79243
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