Drug that blocks the release of calcium from the sarcoplasmic reticulum of skeletal muscle. Ryanodine-binding proteins have also been found in the CNS.
Ryanodine is a poisonous alkaloid found in the South American plant Ryania speciosa (Salicaceae). It was originally used as an insecticide. The compound has extremely high affinity to the open-form ryanodine receptor, a group of calcium channels found in skeletal muscle, smooth muscle, and heart muscle cells. It binds with such high affinity to th...Found on http://en.wikipedia.org/wiki/Ryanodine
<drug> A drug that blocks the release of calcium from the sarcoplasmic reticulum of skeletal muscle. Ryanodine binding proteins have also been found in the CNS. ... (17 Dec 1997) ... Found on http://www.encyclo.co.uk/local/20973
Type: Term Pronunciation: rī-an′ō-dēn Definitions: 1. An alkaloid obtained from Ryania speciosa (family Flacourtiaceae); has a disruptive effect on calcium storage in cardiac and skeletal muscle, where it produces sustained contractions; used as an insecticide.Found on http://www.medilexicon.com/medicaldictionary.php?t=79243
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