Ristocetin is an antibiotic, obtained from Amycolatopsis lurida, previously used to treat staphylococcal infections. It is no longer used clinically because it caused thrombocytopenia and platelet agglutination. It is now used solely to assay those functions in vitro in the diagnosis of conditions such as von Willebrand disease (vWD) and Bernard-S...
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<protein> Mixture of ristocetins A & B: isolated from actinomycete, Nocardia lurida. Induces platelet aggregation. ... (18 Nov 1997) ...
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Mixture of ristocetins A and B: isolated from actinomycete, Nocardia lurida . Induces platelet aggregation.
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Type: Term Pronunciation: ris′tō-sē′tin Definitions: 1. An antibiotic produced by the fermentation of Amycolatopsis orientalis lurida, comprising two substances; ristocetin A and ristocetin B; although no longer used, it causes platelet agglutination and blood coagulation and was used to assay those functions. Synonyms: ristom...
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