
Profilin is an actin-binding protein involved in the dynamic turnover and restructuring of the actin cytoskeleton. It is found in all eukaryotic organisms in most cells. Profilin is important for spatially and temporally controlled growth of actin microfilaments, which is an essential process in cellular locomotion and cell shape changes. This res...
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http://en.wikipedia.org/wiki/Profilin

<cell biology> Actin binding protein (15 kD) that forms a complex with G actin rendering it incompetent to nucleate F actin formation. The profilin actin complex seems to interact with inositol phospholipids that may regulate the availability of nucleation competent G actin. ... (18 Nov 1997) ...
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http://www.encyclo.co.uk/local/20973

Actin-binding protein (15 kD) that forms a complex with G-actin rendering it incompetent to nucleate F-actin formation. The profilin-actin complex seems to interact with inositol phospholipids that may regulate the availability of nucleation-competent G-actin.
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Type: Term Pronunciation: prō-fil′in Definitions: 1. A small protein that binds to monomeric actin (thus becoming profilactin), preventing premature polymerization of actin. It also participates in the inhibition of one isoform of phospholipase C.
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http://www.medilexicon.com/medicaldictionary.php?t=72575
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