<biochemistry> Macromolecule carrying many negative charges. The commonest in cell biological systems is nucleic acid. ... (11 Jan 1998) ... 
Macromolecule carrying many negative charges. The commonest in cell-biological systems is nucleic acid.
Type: Term Pronunciation: pol′ē-an′ī-on Definitions: 1. Anionic sites on proteoglycans in the renal glomeruli that restrict filtration of anionic molecules and facilitate filtration of cationic proteins; loss of polyanion may cause albuminuria in lipoid nephrosis.