Perforin-1 is a protein that in humans is encoded by the PRF1 gene. == Function == Perforin is a cytolytic protein found in the granules of Cytotoxic T lymphocytes (CTLs) and NK cells. Upon degranulation, perforin inserts itself into the target cell`s plasma membrane, forming a pore. The lytic membrane-inserting part of perforin is the MACPF doma....
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http://en.wikipedia.org/wiki/Perforin
<protein> Perforins 1 and 2 form tubular transmembrane complexes (16nm diameter) at the sites of target cell lysis by natural killer cells and cytotoxic T-cells. ... (10 Jan 1998) ...
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http://www.encyclo.co.uk/local/20973
Type: Term Pronunciation: per′fōr-in Definitions: 1. A protein found in the cytoplasmic granules of both T-cytotoxic lymphocytes and natural killer cells. This protein is implicated in target cell lysis by the above cells.
Found on
http://www.medilexicon.com/medicaldictionary.php?t=66868
compound released from a natural killer cell that creates pores in the target cell through which other toxins (particularly granzymes) can gain access to the cytoplasm
Found on
https://courses.lumenlearning.com/microbiology/chapter/glossary/
No exact match found.
