Nogalamycin is an anthracycline antibiotic produced by soil bacteria Streptomyces nogalater. It has antitumor properties but it is also highly cardiotoxic. Less cardiotoxic semisynthetic analog menogaril was developed in the 1970s. Currently nogalamycin or menogaril aren`t used clinically. ...
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<chemical> An antineoplastic agent from a streptomyces nogalater variant. It is a cytolytic antibiotic that inhibits DNA-dependent RNA synthesis by binding to DNA and has some antibacterial action. ... Pharmacological action: antibiotics, anthracycline, intercalating agents, nucleic acid synthesis inhibitors. ... Chemical name: 2,6-Epoxy-2H-n...
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