(from the article `metabolism`) ...of fumarate in a reaction catalyzed by fumarase [45]; this type of reaction also occurred in step [39] of the cycle. The product of reaction [45] ... ...like oxaloacetate, is the anion of an -oxoacid and thus can condense, in a reaction catalyzed by malate synthase, with acetyl coenzyme A; the ... .... Found on http://www.britannica.com/eb/a-z/m/18