
Proteins that form the nuclear lamina, a polymeric structure intercalated between chromatin and the inner nuclear envelope. Lamins A and C (70 and 60 kD respectively) have C terminal sequences homologous to the head and tail domains of keratins, their peptide maps are similar and significantly different from that of lamin B (67 kD), although there ...
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Proteins that form the nuclear lamina, a polymeric structure intercalated between chromatin and the inner nuclear envelope. Lamins A and C (70 and 60 kD respectively) have C-terminal sequences homologous to the head and tail domains of keratins; their peptide maps are similar, and significantly different from that of lamin B (67 kD), although there are some common epitopes.
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Type: Term Pronunciation: lam′inz Definitions: 1. Fibrous network of intermediate filaments associated with the nucleoplasmic aspect of the inner membranes of cell nuclei, composed of polypeptides of varying molecular weights (60,000-80,000) and classified as A, B, C, and upward, on the basis of physical properties; the phosphorylation of lam...
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http://www.medilexicon.com/medicaldictionary.php?t=47890
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