2-Iodoacetamide is an alkylating agent used for peptide mapping purposes. Its actions are similar to those of iodoacetate. It is commonly used to bind covalently with the thiol group of cysteine so the protein cannot form disulfide bonds. Also used in ubiquitin studies as an inhibitor of deubiquitinase enzymes (DUBs) because it alkylates the cyste...
Found on
http://en.wikipedia.org/wiki/Iodoacetamide
<chemical> 2-iodoacetamide. An alkylating sulfhydryl reagent. Its actions are similar to those of iodoacetate. ... Pharmacological action: enzyme inhibitors, alkylating agents, sulfhydryl reagents. ... Chemical name: Acetamide, 2-iodo- ... (12 Dec 1998) ...
Found on
http://www.encyclo.co.uk/local/20973
Type: Term Pronunciation: ī-ō′dō-ă-sē′tă-mīd Definitions: 1. a cerivative of acetamide that reacts readily with sulfhydryl groups and is therefore a strong inhibitor of many enzymes.
Found on
http://www.medilexicon.com/medicaldictionary.php?t=45552
No exact match found.
