Retroviral integrase (IN) is an enzyme produced by a retrovirus (such as HIV) that enables its genetic material to be integrated into the DNA of the infected cell. Retroviral INs are not to be confused with phage integrases, such as λ phage integrase (Int) (see site-specific recombination). IN is a key component in the retroviral pre-integration ...
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http://en.wikipedia.org/wiki/Integrase
<enzyme> The HIV enzyme that inserts HIV's genes into a cells normal DNA. ... Integrase operates after reverse transcriptase has created a DNA version of the RNA form of HIV genes present in virus particles. Drugs that block the action of integrase are under development. ... (18 Nov 1997) ...
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http://www.encyclo.co.uk/local/20973
The HIV enzyme that governs the insertion of HIV's proviral genetic material into the host genome. Integrase is a target for a new generation of HIV drugs.
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http://www.virology.net/ATVGlossary.html
No exact match found.
