In molecular biology, immunophilins are endogenous cytosolic peptidyl-prolyl isomerases that {sic|interconvert} between the cis and trans positions. Immunophilins are targeted by immunosuppressive drugs such as Sirolimus (earlier rapamycin), cyclosporine, and tacrolimus. For these drugs in particular, known immunophilins such as cyclophilin cataly...
Found on
http://en.wikipedia.org/wiki/Immunophilins
Type: Term Pronunciation: im′yū-nō-fil′inz Definitions: 1. High-affinity receptor proteins in the cytoplasm that combine with immunosuppressant drugs leading to rotamase inhibition and, in T cells, thus to interruption of cell activation.
Found on
http://www.medilexicon.com/medicaldictionary.php?t=43761
No exact match found.
