Type: Term Pronunciation: hī′drō-lās-ĕz Definitions: 1. Enzymes (EC class 3) cleaving substrates with addition of H2O at the point of cleavage, esterases, phosphatases, nucleases, peptidases. Synonyms: hydrolyzing enzymes Found on http://www.medilexicon.com/medicaldictionary.php?t=41955