Referring to the binding of the same ligand to a macromolecule; e.g., the binding of four O2 to haemoglobin is homotropic cooperativity. ... (05 Mar 2000) ... 
Type: Term Pronunciation: hō′mō-trō′pik Definitions: 1. Referring to the binding of the same ligand to a macromolecule; the binding of four O2 to hemoglobin is homotropic cooperativity.
homotropic A reference to a flower fertilized by its own pollen.