1) Homeobox gene 2) Homeotic gene
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https://www.crosswordclues.com/clue/homeobox
A homeobox is a DNA sequence found within genes that are involved in the regulation of patterns of anatomical development (morphogenesis) in animals, fungi and plants. == Discovery == They were discovered independently in 1983 by Ernst Hafen, Michael Levine, and William McGinnis working in the lab of Walter Jakob Gehring at the University of Basel...
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http://en.wikipedia.org/wiki/Homeobox
(from the article `evolution`) The critical region of the proteins is encoded by a sequence of about 180 consecutive nucleotides (called the homeobox). The corresponding protein ...
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http://www.britannica.com/eb/a-z/h/65
<molecular biology> Conserved DNA sequence originally detected by DNA hybridisation in many of the genes that give rise to homeotic and segmentation mutants in Drosophila. ... The homeobox consists of about 180 nucleotides coding for a sequence of 60 amino acids in a protein, sometimes termed the homeodomain, of which about 80-90% are identic...
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http://www.encyclo.co.uk/local/20973
A short stretch of nucleotides whose base sequence is virtually identical in all the genes that cont
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http://www.encyclo.co.uk/local/22391
(= homoeobox) Conserved DNA sequence originally detected by DNA-DNA hybridization in many of the genes that give rise to homeotic mutants and segmentation mutants in Drosophila . The homeobox consists of about 180 nucleotides coding for a sequence of 60 amino acids in a protein, sometimes termed the homeodomain, of which about 80-90% are identical in the various homeodomains identified from Drosophila . Homeoboxes have also been detected in the genomes of vertebrates, with about 75% amino acid homology and a similar sequence has been found in the MAT gene of yeast. The homeobox codes for a protein domain that is involved in binding to DNA. Three subfamilies of homeobox-containing proteins can be identified, based on the archetypal Drosophila genes engrailed , antennapedia and paired . Interestingly, linear order within genome maps to order of expression in embryo. This may be required for the transcriptional silencing of certain homeotic genes (see Polycomb > Polycomb).
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http://www.encyclo.co.uk/visitor-contributions.php
Type: Term Pronunciation: hō′mē-ō-boks Definitions: 1. A highly conserved DNA sequence of about 180 base pairs near the 3′ end of specific homeotic genes; it encodes a DNA-binding domain that allows the homeobox proteins to bind to and regulate gene expression in development. Synonyms: homeodomain
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http://www.medilexicon.com/medicaldictionary.php?t=41296
homeobox gene noun one of various similar homeotic genes that are involved in bodily segmentation during embryonic development
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https://www.encyclo.co.uk/local/20974
A short stretch of nucleotides whose base sequence is virtually identical in all the genes that contain it. It has been found in many organisms from fruit flies to human beings. In the fruit fly, a homeobox appears to determine when particular groups of genes are expressed during development.
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https://www.encyclo.co.uk/local/21029
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