Heparanase, also known as HPSE, is an enzyme that acts both at the cell-surface and within the extracellular matrix to degrade polymeric heparan sulfate molecules into shorter chain length oligosaccharides. ==Synthesis and structure== The protein is originally synthesised in an inactive 65 kDa proheparanase form in the golgi apparatus and transfer...
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http://en.wikipedia.org/wiki/Heparanase
<enzyme> Tumour cell enzyme has endoglycosidase activity which degrades glycosaminoglycans into fragments of intermediate size ... Registry number: EC 3.2.1.- ... (26 Jun 1999) ...
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http://www.encyclo.co.uk/local/20973
Type: Term Pronunciation: hep′ar-i-nās Definitions: 1. An enzyme capable of disrupting the heparan sulfate structure of basement membranes and other entities, expressed in cancer cells.
Found on
http://www.medilexicon.com/medicaldictionary.php?t=40312
No exact match found.
