Filipin is a mixture of chemical compounds first isolated by chemists at the Upjohn company in 1955 from the mycelium and culture filtrates of a previously unknown actinomycete, Streptomyces filipinensis. It was discovered in a soil sample collected in the Philippine Islands, hence the name filipin. The isolate possessed potent antifungal activity...
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http://en.wikipedia.org/wiki/Filipin
<chemical> 4,6,8,10,12,14,16,27-octahydroxy-3-(1-hydroxyhexyl)-17,28-dimethoxyoxacyclooctacosa-17,19,21,23,25-pentaen-2-one (filipin III). A complex of polyene antibiotics obtained from streptomyces filipinensis. Filipin III alters membrane function by interfering with membrane sterols, inhibits mitochondrial respiration, and is proposed as a...
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http://www.encyclo.co.uk/local/20973
Polyene antibiotic from Streptomyces filipinensis . Polymers of filipin associated with cholesterol in the cell membrane form pores which lead to cytolysis (as does amphotericin B)
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http://www.encyclo.co.uk/visitor-contributions.php
No exact match found.
