Etretinate definitions

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Etretinate

Etretinate logo #21000 ==Properties== Etretinate has a low therapeutic index and a long elimination half-life (t1/2) of 120 days, which make dosing difficult. Etretinate is an aromatic retinoid, and therefore highly lipophilic. It is stored and released from adipose tissue, so its effects can continue long after dosage stops. It is detectable in the plasma for up to thr...
Found on http://en.wikipedia.org/wiki/Etretinate

etretinate

etretinate logo #20973<chemical> An oral retinoid used in the treatment of keratotic genodermatosis, lichen planus, and psoriasis. Beneficial effects have also been claimed in the prophylaxis of epithelial neoplasia. The compound may be teratogenic. ... Pharmacological action: keratolytic agents. ... Chemical name: 2,4,6,8-Nonatetraenoic acid, 9-(4-methoxy-2,3,6-t...
Found on http://www.encyclo.co.uk/local/20973
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