
Endothelins are proteins that constrict blood vessels and raise blood pressure. They are normally kept in balance by other mechanisms, but when they are over-expressed, they contribute to high blood pressure (hypertension) and heart disease. Endothelins are 21-amino acid vasoconstricting peptides produced primarily in the endothelium having a key ...
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http://en.wikipedia.org/wiki/Endothelin

<protein> Group of peptide hormones released by endothelial cells. The most potent vasoconstrictor hormones known. Structurally related to the snake venom sarafotoxins. ... (18 Nov 1997) ...
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http://www.encyclo.co.uk/local/20973

Type: Term Pronunciation: en′dō-thē′lin Definitions: 1. A 21-amino acid peptide originally derived from endothelial cells. It is an extremely potent vasoconstrictor. Three different gene products have been identified, endothelin 1, endothelin 2, and endothelin 3; they are found in brain, kidney, and endothelium (endothelin 1),...
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http://www.medilexicon.com/medicaldictionary.php?t=29209

Group of peptide hormones produced by the vascular epithelium (walls of the blood vessels). When released it acts directly on the walls of blood vessels to cause vasoconstriction. It is the most potent vasoconstrictor known.
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https://www.encyclo.co.uk/local/20737
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