(doun″reg-u-la´shәn) controlled decrease, particularly decrease in expression of a gene in response to cellular or environmental factors, as by a decrease in transcription of the gene or by destabilization of mRNA, or the reduction in responsiveness of a cell to stimulatory factors after a first exposure, as...
Found on
http://www.encyclo.co.uk/local/21001
Downregulation: An decrease in the number of receptors on the surface of target cells, making the cells less sensitive to a hormone or another agent. Some receptors can be rapidly down regulated.
Found on
http://www.medterms.com/script/main/art.asp?articlekey=24471
No exact match found.
