It is marketed under the trade name Tikosyn by Pfizer, and is available in the United States in capsules containing 125, 250, and 500 µg of dofetilide. Due to the pro-arrhythmic potential of dofetilide, it is only available by prescription by physicians who have undergone specific training in the risks of treatment with dofetilide. In addition, i...
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(do-fet´ә-līd) an antiarrhythmic that prolongs the duration of the cardiac action potential and the effective refractory period without affecting conduction velocity; used in the treatment of atrial arrhythmias, administered orally.
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