Dideoxynucleotides are chain-terminating inhibitors of DNA polymerase, used in the Sanger method for DNA sequencing. They are also known as 2`,3` dideoxynucleotides, and abbreviated as ddNTPs (ddGTP, ddATP, ddTTP and ddCTP). The absence of the 3`-hydroxyl group means that, after being added by a DNA polymerase to a growing nucleotide chain, no ......
Found on
http://en.wikipedia.org/wiki/Dideoxynucleotide
<biochemistry> A deoxynucleotide that lacks a 3' hydroxyl group, and is thus unable to form a 3'-5' phosphodiester bond necessary for chain elongation. Dideoxynucleotides are used in DNA sequencing and the treatment of viral diseases. ... (09 Oct 1997) ...
Found on
http://www.encyclo.co.uk/local/20973
No exact match found.
