Depurination is a chemical reaction of purine deoxyribonucleosides, deoxyadenosine and deoxyguanosine, and ribonucleosides, adenosine or guanosine, in which the β-N-glycosidic bond is hydrolytically cleaved releasing a nucleic base, adenine or guanine, respectively. The second product of depurination of deoxyribonucleosides and ribonucleosides is...
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http://en.wikipedia.org/wiki/Depurination
<biochemistry, molecular biology> The N glycosidic link between purine bases and deoxyribose in DNA has an appreciable rate of spontaneous cleavage in vivo, a lesion that must be enzymically repaired to ensure stability of the genetic information. ... (18 Nov 1997) ...
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http://www.encyclo.co.uk/local/20973
(of DNA) The N-glycosidic link between purine bases and deoxyribose in DNA has an appreciable rate of spontaneous cleavage in vivo , a lesion that must be enzymically repaired to ensure stability of the genetic information.
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http://www.encyclo.co.uk/visitor-contributions.php
Type: Term Pronunciation: dē-pyūr-i-nā′shŭn Definitions: 1. A major degradation process occurring in exposed DNA (in fossils).
Found on
http://www.medilexicon.com/medicaldictionary.php?t=23855
No exact match found.
