Cyclins are a family of proteins that control the progression of cells through the cell cycle by activating cyclin-dependent kinase (Cdk) enzymes. == Function == Cyclins were originally named because their concentration varies in a cyclical fashion during the cell cycle. (Note that the cyclins are now classified according to their conserved cyclin...
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<protein> Proteins (A and B forms known) whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are though to drive cells into G2 phase and thus to mitosis. Cyclins combine with p34 kinase (cdc2) to form maturation-promoting factor (M...
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Proteins (A and B forms known) whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are thought to drive cells into G2 phase and thus towards mitosis. Cyclins combine with p34 kinase (cdc2) to form maturation promoting factor (MPF). See also M-phase promoting factor, cyclin-dependent kinase (cdk), cdk inhibitors, cdk activating kinase.
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Type: Term Pronunciation: sī′klin Definitions: 1. A class of proteins involved in regulation of the cell cycle.
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Cyclin: One of a group of proteins that regulate the cell cycle. The cyclins bind to and activate cyclin-dependent kinases. The cyclins include cyclin A, cyclin B, cyclin C, cyclin D, cyclin E, cyclin F, cyclin G, cyclin H, cyclin K, and cyclin T.
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A protein found in the dividing cells of many organisms that acts as a control during cell division.
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