Regular periodic sub-membranous arrays of vinculin in muscle cells; link sarcomeres to the membrane and are associated with links to extracellular matrix.
The costamere is a structural-functional component of striated muscle cells which connects the sarcomere of the muscle to the cell membrane. Costameres are sub-sarcolemmal protein assemblies circumferentially aligned in register with the Z-disk of peripheral myofibrils. They physically couple force-generating sarcomeres with the sarcolemma in stri...Found on http://en.wikipedia.org/wiki/Costamere
<cell biology> Regular periodic sub membranous arrays of vinculin in muscle cells, link sarcomeres to the membrane and are associated with links to extracellular matrix. ... (18 Nov 1997) ... Found on http://www.encyclo.co.uk/local/20973
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