Carbimazole is used to treat hyperthyroidism. Carbimazole is a pro-drug as after absorption it is converted to the active form, methimazole. Methimazole prevents the thyroid peroxidase enzyme from coupling and iodinating the tyrosine residues on thyroglobulin, hence reducing the production of the thyroid hormones T3 and T4 (thyroxine). ==Clinical ...
Found on
http://en.wikipedia.org/wiki/Carbimazole
(from the article `hyperthyroidism`) ...a chronic, even lifelong, disorder. It can be treated with an antithyroid drug, radioactive iodine, or surgery (thyroidectomy). There are three ...
Found on
http://www.britannica.com/eb/a-z/c/22
<chemical> An imidazole antithyroid agent. Carbimazole is metabolised to methimazole, which is responsible for the antithyroid activity. ... Pharmacological action: antithyroid agents. ... Chemical name: 1H-Imidazole-1-carboxylic acid, 2,3-dihydro-3-methyl-2-thioxo-, ethyl ester ... (12 Dec 1998) ...
Found on
http://www.encyclo.co.uk/local/20973
No exact match found.
