A group of functionally related glycoproteins responsible for the calcium-dependent cell-to-cell adhesion mechanism. They are divided into subclasses e-, p-, and n-cadherins, which are distinct in immunological specificity and tissue distribution. They promote cell adhesion via a homophilic mechanism. These compounds play a role in the construction...
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http://www.encyclo.co.uk/local/20973
Integral membrane proteins involved in calcium dependent cell adhesion. There are three types, named after their distributions: N-cadherin (neural); E-cadherin (epithelial) (equivalent to uvomorulin and L-CAM); and P-cadherin (placental). Formed of a 600 amino acid extracellular domain, containing 4 repeats believed to contain the Ca2+ binding sites, a transmembrane domain, and a 150 amino acid intracellular domain.
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No exact match found.
