1) Animal disease 2) Conceit 3) Sign of conceit 4) Slang for an egoist 5) Swollen ego 1) Ego 
Bighead is a graphic novel written and illustrated by Jeffrey Brown and published by Top Shelf Productions. The title character is a superhero whose main power seems to be the fact that he has a giant head. Unlike many of Brown`s other graphic novels, Bighead is not an autobiographical work, but rather a parody of classic superhero stories. Bighe....
Bighead is slang for an egoist.
[n] - any of various diseases of animals characterized by edema of the head and neck
noun any of various diseases of animals characterized by edema of the head and neck
an excessive estimate of one's importance; conceit. · · an inflammatory swelling of the tissues of the head of sheep, caused by the anaerobic bacillus Clostridium novyi. · enlargement of the head and jawbones of horses resulting from nutritional hyperthyroidism.