Bicuculline is a light-sensitive competitive antagonist of GABAA receptors. It was originally identified in 1932 in plant alkaloid extracts and has been isolated from Dicentra cucullaria, Adlumia fungosa, Fumariaceae, and several Corydalis species. Since it blocks the inhibitory action of GABA receptors, the action of bicuculline mimics epilepsy. ...
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http://en.wikipedia.org/wiki/Bicuculline
<drug> From Dicentra cucullaria and herbs of the genus Corydalis. Specific blocking agent for the action of the amino acid transmitter _ aminobutyric acid (GABA). ... See: amino acid transmitter, amino acid receptor superfamily, GABAA receptor. ... (18 Nov 1997) ...
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http://www.encyclo.co.uk/local/20973
From Dicentra cucullaria and herbs of the genus Corydalis . Specific blocking agent for the action of the amino acid transmitter g -aminobutyric acid (GABA). See amino acid transmitter; amino acid receptor superfamily, GABA receptor.
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Type: Term Pronunciation: bī′kū-kyū′lēn Definitions: 1. An alkaloid naturally occurring in the d-form; found in Dicentra cucullaria and Adlumia fungosa (family Fumariaceae) and several Corydalis species; a powerful convulsant that acts by antagonizing γ-aminobutyric acid, an inhibitory neurotransmitter.
Found on
http://www.medilexicon.com/medicaldictionary.php?t=10114
No exact match found.
