If terminal sialic acid residues are removed from glycoproteins, the resulting proteins are known as asialoglycoproteins. The exposure of the subterminal galactose residues results in rapid clearance of the glycoproteins from the circulation through hepatocyte asialoglycoprotein receptors on Kuppfer cells. ...
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http://en.wikipedia.org/wiki/Asialoglycoprotein
<protein> The carbohydrate moiety of many vertebrate glycoproteins bears terminal residues of sialic acid. ... If such residues are removed, for example by treatment with a neuraminidase, the resulting proteins are known as asialoglycoproteins. In the case of certain plasma proteins, the asialo derivatives are specifically bound by a receptor...
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http://www.encyclo.co.uk/local/20973
The carbohydrate moiety of many vertebrate glycoproteins bears terminal residues of sialic acid. If such residues are removed, eg. by treatment with a neuraminidase, the resulting proteins are known as asialoglycoproteins. In the case of certain plasma proteins, the asialo-derivatives are specifically bound by a receptor on the surface of liver parenchymal cells (the scavenger receptor).
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http://www.encyclo.co.uk/visitor-contributions.php
Type: Term Pronunciation: ā′sī-al′ō-glī′kō-prō′tēn Definitions: 1. A glycoprotein without a sialic acid moiety; such proteins are recognized by asialoglycoprotein receptors and are targeted for degradation.
Found on
http://www.medilexicon.com/medicaldictionary.php?t=7892
No exact match found.
