Antifolate definitions

Antifolate

1) Folic acid antagonist
Found on https://www.crosswordclues.com/clue/antifolate

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Antifolate

Antifolates are drugs that antagonise (that is, block) the actions of folic acid (vitamin B9). Folic acid`s primary function in the body is as a cofactor to various methyltransferases involved in serine, methionine, thymidine and purine biosynthesis. Consequently antifolates inhibit cell division, DNA/RNA synthesis and repair and protein synthesi....
Found on http://en.wikipedia.org/wiki/Antifolate

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antifolate

A substance that blocks the activity of folic acid. Antifolates are used to treat cancer. Also called folate antagonist.
Found on http://www.cancer.gov/dictionary?expand=A

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antifolate

(an″tĭ-fo´lāt) folic acid antagonist.
Found on http://www.encyclo.co.uk/local/21001

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