Aminopterin (4-aminopteroic acid), a 4-amino analog of folic acid, is an antineoplastic drug with immunosuppressive properties used in chemotherapy. Aminopterin is a synthetic derivative of pterin. Aminopterin works as an enzyme inhibitor by competing for the folate binding site of the enzyme dihydrofolate reductase. Its binding affinity for dihyd...
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http://en.wikipedia.org/wiki/Aminopterin
An anticancer drug that belongs to the family of drugs called antimetabolites.
Found on
http://www.cancer.gov/dictionary?expand=A
<drug> A folic acid analogue and inhibitor of dihydrofolate reductase. A potent cytotoxic agent used in the treatment of acute leukaemia. ... (18 Nov 1997) ...
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http://www.encyclo.co.uk/local/20973
A folic acid analogue and inhibitor of dihydrofolate reductase. A potent cytotoxic agent used in the treatment of acute leukaemia.
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http://www.encyclo.co.uk/visitor-contributions.php
A folic acid antagonist that is used as a cancer chemotherapeutic agent or to induce abortion. When taken during the first trimester of pregnancy or unsuccesfully to inudce abortion, the drug will cause fetal malformations.
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http://www.pregnology.com/
No exact match found.
