Transdifferentiation, also known as lineage reprogramming, is a process where one mature somatic cell transforms into another mature somatic cell without undergoing an intermediate pluripotent state or progenitor cell type. It is a type of metaplasia, which includes all cell fate switches, including the interconversion of stem cells. Current uses ...
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<cell biology> Change of a cell or tissue from one differentiated state to another. Rare and has mainly been observed with cultured cells. ... <zoology> In newts the pigmented cells of the iris transdifferentiate to form lens cells if the existing lens is removed. ... (17 Mar 1998) ...
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Change of a cell or tissue from one differentiated state to another. Rare, and has mainly been observed with cultured cells. In newts the pigmented cells of the iris transdifferentiate to form lens cells if the existing lens is removed.
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Transdifferentiation: 1. The change of a cell or tissue from one differentiated state to another. 2. The differentiation of a tissue-specific stem cell into another type of cell as, for example, a bone marrow stem cell differentiating into a neuron.
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