Tau proteins (or τ proteins, after the Greek letter by that name) are proteins that stabilize microtubules. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. Pathologies and dementias of the nervous system such as Alzheimer`s....
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http://en.wikipedia.org/wiki/Tau_protein
<cell biology> Protein (60-70 kD) that co purifies with tubulin through cycles of assembly and disassembly and the first microtubule associated protein to be characterised. Tau proteins are a family made by alternative splicing of a single gene. It has tandem repeats of a tubulin binding domain and promotes tubulin assembly. Although tau prot...
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http://www.encyclo.co.uk/local/20973
[tubulin-associated] any of a family of vertebrate microtubule-associated proteins that promote microtubule assembly and stability; they are found in all cells but are particularly associated with axons of neurons. Abnormally hyperphosphorylated forms are a major component of the paired helical filaments found in neurof...
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http://www.encyclo.co.uk/local/21001
(= tau factor) Protein (60-70 kD) that co-purifies with tubulin through cycles of assembly and disassembly, and the first microtubule associated protein to be characterized. Tau proteins are a family made by alternative splicing of a single gene. It has tandem repeats of a tubulin binding domain and promotes tubulin assembly. Although tau proteins are found in all cells they are major components of neurons where they are predominantly associated with microtubules of the axon. See MAPs.
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http://www.encyclo.co.uk/visitor-contributions.php
Type: Term Definitions: 1. microtubule-associated protein that accumulates in neurons in neurofibrillary degeneration in a wide variety of disorders including Alzheimer disease; gene for tau protein situated on chromosome 17; normal role for tau protein is to stabilize microtubules; abnormal phosphorylation of tau protein destabilizes microtubules,...
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http://www.medilexicon.com/medicaldictionary.php?t=73051
The major protein that makes up neurofibrillary tangles found in degenerating nerve cells.
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https://www.encyclo.co.uk/local/23246
No exact match found.
