Tanespimycin (17-``N``-allylamino-17-demethoxygeldanamycin, 17-AAG) is a derivative of the antibiotic geldanamycin that is being studied in the treatment of cancer, specific young patients with certain types of leukemia or solid tumors, especially kidney tumors. It works by inhibiting Hsp90, which is expressed in those tumors. It belongs to th...
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http://en.wikipedia.org/wiki/Tanespimycin
A substance being studied in the treatment of cancer. It is made from an antibiotic called geldanamycin. Tanespimycin helps cause the breakdown of certain proteins in the cell, and may kill cancer cells. It is a type of antineoplastic antibiotic and a type of HSP90 inhibitor. Also called 17-AAG and 17-N-allylamino-17-demethoxygeldanamycin.
Found on
http://www.cancer.gov/dictionary?expand=T
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