(pral″ĭ-doks┬┤ēm) a cholinesterase reactivator whose salts are used in treatment of organophosphorus compound poisoning; it also has limited value in counteracting overdosage of carbamate-type cholinesterase inhibitors in persons being treated for myasthenia gravis.
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Pralidoxime (2-pyridine aldoxime methyl chloride,) or 2-PAM, usually as the chloride or methiodide salts, belongs to a family of compounds called oximes that bind to organophosphate-inactivated acetylcholinesterase. It is used to combat poisoning by organophosphates or acetylcholinesterase inhibitors (nerve agents) in conjunction with atropine and...
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