Photolyases (EC 4.1.99.3) are DNA repair enzymes that repair damage caused by exposure to ultraviolet light. This enzyme mechanism requires visible light, preferentially from the violet/blue end of the spectrum, and is known as photoreactivation. Photolyase is a phylogenetically old enzyme which is present and functional in many species, from the ...
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http://en.wikipedia.org/wiki/Photolyase
(from the article `genetic disease, human`) Ultraviolet light, when acting on DNA, can lead to covalent linking of adjacent pyrimidine bases. Such pyrimidine dimerization is mutagenic, but this ...
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http://www.britannica.com/eb/a-z/p/60
See: deoxyribodipyrimidine photolyase. ... Origin: photo-+ G. Lyo, to loosen, + -ase ... (05 Mar 2000) ...
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http://www.encyclo.co.uk/local/20973
(= DNA photolyase) Family of ubiqitous enzymes found in bacteria, archaebacteria and eukaryotes that can repair UV-induced DNA damage. The protein (between 454 to 614 residues) is associated with two prosthetic groups, FADH and a light-harvesting cofactor, MTHF (5,10-methenyltetrahydofolyl polyglutamate). Light is needed for the repair step.
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http://www.encyclo.co.uk/visitor-contributions.php
Type: Term Pronunciation: fō′tō-lī′ās See: deoxyribodipyrimidine photolyase
Found on
http://www.medilexicon.com/medicaldictionary.php?t=68625
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