Molsidomine is an orally active, long acting vasodilating drug. Molsidomine is metabolized in the liver to the active metabolite linsidomine. Linsidomine is an unstable compound that releases nitric oxide (NO) upon decay as the actual vasodilating compound. ==Release of nitric oxide== Molsidomine → Linsidomine (SIN-1) → SIN-1A → nitric oxide...
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<chemical> 3-ethyl-1,5,6,7-tetrahydro-2-methyl-5-(morpholinylmethyl)- 4h-indol-4-one. A vasodilator that has been used in angina pectoris. Concerns regarding the carcinogenicity or molsidomine have been raised and marketing has been suspended on two occasions. ... Pharmacological action: vasodilator agents. ... Chemical name: Sydnone imine, N...
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