Midkine (MK or MDK) also known as neurite growth-promoting factor 2 (NEGF2) is a protein that in humans is encoded by the MDK gene. Midkine is a basic heparin-binding growth factor of low molecular weight, and forms a family with pleiotrophin (NEGF1, 46% homologous with MK). It is a nonglycosylated protein, composed of two domains held by disulfid...
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http://en.wikipedia.org/wiki/Midkine
<growth factor> Heparin binding growth factor (13 kD) of the TGF superfamily, has 50% sequence identity with Heparin Binding Growth Associated Molecule (HB GAM). Structurally unrelated to FGF. Midkine was originally described as associated with tooth morphogenesis induced by epithelial mesenchyme interactions. Nucleolin binds midkine. ... (18...
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http://www.encyclo.co.uk/local/20973
Heparin-binding growth factor (13 kD) of the TGF- b ; superfamily; has 50% sequence identity with heparin-binding growth-associated molecule (HB-GAM). Structurally unrelated to fibroblast growth factor (FGF). Midkine was originally described as associated with tooth morphogenesis induced by epithelial-mesenchyme interactions. Nucleolin binds midkine.
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http://www.encyclo.co.uk/visitor-contributions.php
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