Maytansine (USAN), or maitansine (INN), is a cytotoxic agent. It inhibits the assembly of microtubules by binding to tubulin at the rhizoxin binding site. It is a macrolide of the ansamycin type and can be isolated from plants of the genus Maytenus. Derivatives are known as maytansinoids. ...
Found on
http://en.wikipedia.org/wiki/Maytansine
<chemical> An ansa macrolide isolated from the east african shrubs maytenus serrata and m. Buchananii. It has antineoplastic activity, probably due to its inhibition of DNA synthesis. ... Pharmacological action: antineoplastic agent, phytogenic, nucleic acid synthesis inhibitors. ... Chemical name: Maytansine ... (12 Dec 1998) ...
Found on
http://www.encyclo.co.uk/local/20973
No exact match found.
