The antigenic specificities defined by the unique sequences (idiotopes) of the antigen combining site. Thus anti-idiotype antibodies combine with those specific sequences, may block immunological reactions, and may resemble the epitope to which the first antibody reacts.
In immunology, an idiotype is a shared characteristic between a group of immunoglobulin or T cell receptor (TCR) molecules based upon the antigen binding specificity and therefore structure of their variable region. The word idiotype comes from two Greek roots, idio meaning `private, distinctive, peculiar` and typos meaning `mark.` Thus idioty...Found on http://en.wikipedia.org/wiki/Idiotype
idiotype The total hereditary determinants of an individual, comprising both chromosomal and extrachromosomal factors.Found on http://www.wordinfo.info/words/index/info/view_unit/2794/5
The antigenic specificites defined by the unique sequences (idiotopes) of the antigen combining site. Thus anti-idiotype antibodies combine with those specific sequences, may block immunological reactions and may resemble the epitope to which the first antibody reacts. ... (18 Nov 1997) ... Found on http://www.encyclo.co.uk/local/20973
The combined antigenic determinants (idiotopes) found on antibodies of an individual that are directed at a particular antigen; such antigenic determinants are found only in the variable region.
Found on http://www.encyclo.co.uk/local/21016
The complete set of idiotopes in the variable region of an antibody or T-cell receptor that react with an anti-idiotypic serum.Found on http://www.roitt.com/glossary.asp
Type: Term Pronunciation: id′ē-ō-tīp Definitions: 1. Collection of idiotopes within the variable region that confers on an immunoglobulin molecule an antigenic specificity and is frequently a unique attribute of a given antibody in a given animal. It is the product of a limited number of B lymphocyte clones; also found on the T...Found on http://www.medilexicon.com/medicaldictionary.php?t=43410
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