entactin

(= nidogen) A dumbbell shaped 150 kD sulphated glycoprotein that is found in all basement membranes. It binds to laminin, forming a very stable 1:1 complex (KD = 10nM) and almost all laminin preparations contain entactin. The N-terminal globular domain can self-aggregate, whilst the C-terminal globular domain binds to the short arm of laminin and to collagen IV. The connecting rod has 5-6 EGF-like domains of cysteine-rich repeats, one of which has an RGD sequence for cellular interaction. ...

Entactin

Entactin also known as nidogen-1 (NID-1) is a protein that in humans is encoded by the NID1 gene. Entactin is a component of the basement membrane alongside other components such as collagen type IV, proteoglycans (heparan sulfate and glycosaminoglycans), laminin and fibronectin. == Function == Entactin is a member of the nidogen family of basemen...
Found on http://en.wikipedia.org/wiki/Entactin

entactin

<protein> A dumbbell shaped 150 kD sulphated glycoprotein that is found in all basement membranes. It binds to laminin, forming a very stable 1:1 complex (KD = 10nM) and almost all laminin preparations contain entactin. The N terminal globular domain can self aggregate, whilst the C terminal globular domain binds to the short arm of laminin a...
Found on http://www.encyclo.co.uk/local/20973

entactin

Type: Term Pronunciation: en-tak′tin Definitions: 1. A glycoprotein that binds to laminin and type IV collagen in the basal lamina of the renal glomerulus and is a major cell attachment factor; entactin is a sulfated calcium-binding protein. Synonyms: nidogen
Found on http://www.medilexicon.com/medicaldictionary.php?t=29339
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